Linsitinib
Linsitinib (OSI-906) is a selective, orally active IGF-1R inhibitor with antitumor potential. It suppresses cancer cell proliferation and promotes apoptosis by blocking IGF-1R signaling, a pathway overactive in many cancers. Its activity has been investigated in preclinical in vitro and in vivo studies across various oncology research fields.
Product Specifications
CAS Number
867160-71-2
Product Name Alternative
OSI-906
Field of Research
Signal Transduction
Purity
>98%
Bioactivity
IGF-1R kinase and InsR kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) .
Smiles
NC=1C=2N (C (=NC2C3=CC4=C (C=C3) C=CC (=N4) C5=CC=CC=C5) [C@H]6C[C@@] (C) (O) C6) C=CN1
Molecular Formula
C26H23N5O
Molecular Weight
421.49
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-[8-Amino-1- (2-phenyl-7-quinolyl) imidazo[1,5-a]pyrazin-3-yl]-1-methyl-cyclobutanol
Available Sizes
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