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ONX-0914

ONX-0914 (PR-957) is a potent and selective inhibitor of the immunoproteasome, demonstrating low activity against constitutive proteasome subunits. This small molecule is widely used in both in vitro and in vivo research to study autoimmune diseases, inflammation, and cancer immunotherapy mechanisms.

Product Specifications

CAS Number

960374-59-8

Product Name Alternative

Bacterial, ONX 0914, ONX0914, ONX-0914, Inhibitor, inhibit, Human immunodeficiency virus, HIV, HIVProtease, HIV Protease, Proteasome, PR957, PR-957, PR 957

Field of Research

Infectious Disease & Virology, Protein Biochemistry

Purity

98.24% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.44 mM) ; DMSO:140 mg/mL (241.1 mM)

Smiles

COc1ccc (C[C@H] (NC (=O) [C@H] (C) NC (=O) CN2CCOCC2) C (=O) N[C@@H] (Cc2ccccc2) C (=O) [C@@]2 (C) CO2) cc1

Molecular Formula

C31H40N4O7

Molecular Weight

580.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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