ONX-0914
ONX-0914 (PR-957) is a potent and selective inhibitor of the immunoproteasome, demonstrating low activity against constitutive proteasome subunits. This small molecule is widely used in both in vitro and in vivo research to study autoimmune diseases, inflammation, and cancer immunotherapy mechanisms.
Product Specifications
CAS Number
960374-59-8
Product Name Alternative
Bacterial, ONX 0914, ONX0914, ONX-0914, Inhibitor, inhibit, Human immunodeficiency virus, HIV, HIVProtease, HIV Protease, Proteasome, PR957, PR-957, PR 957
Field of Research
Infectious Disease & Virology, Protein Biochemistry
Purity
98.24% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.44 mM) ; DMSO:140 mg/mL (241.1 mM)
Smiles
COc1ccc (C[C@H] (NC (=O) [C@H] (C) NC (=O) CN2CCOCC2) C (=O) N[C@@H] (Cc2ccccc2) C (=O) [C@@]2 (C) CO2) cc1
Molecular Formula
C31H40N4O7
Molecular Weight
580.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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