What is the catalog number for Zotarolimus?

The catalog number for Zotarolimus is orb1301133.

What sizes are available for Zotarolimus?

Zotarolimus is available in the following size(s): 1 mg, 5 mg, 10 mg, 1 ml x 10 mM (in DMSO).

How many pack sizes does Zotarolimus come in?

Zotarolimus is available in 4 different pack sizes.

Is Zotarolimus in stock?

Zotarolimus is currently made to order / not held in immediate stock. Contact us for lead time.

Zotarolimus

Zotarolimus (ABT-578) is a rapamycin analog that potently inhibits FKBP-12 with an IC50 of 2.8 nM. It is widely used in cardiovascular and oncology research to study mTOR pathway inhibition in both cellular assays and animal models of restenosis and cancer.

Product Specifications

CAS Number

221877-54-9

Product Name Alternative

Rapamycin, stents, restenosis, Zotarolimus, coronary, disease, drug-eluting, A 179578, A179578, A-179578, ABT578, ABT-578, ABT 578, artery, inhibit, immunosuppressant, FKBP-12, Inhibitor

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Purity

95.00% (May vary between batches)

Solubility

DMSO:93 mg/mL (96.25 mM) ; Ethanol:93 mg/mL (96.25 mM) ;10% DMSO+90% Corn Oil:3.3 mg/mL (3.42 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

[H][C@@]12CC[C@@H] (C) [C@@] (O) (O1) C (=O) C (=O) N1CCCC[C@@]1 ([H]) C (=O) O[C@@] ([H]) (CC (=O) [C@H] (C) \C=C (C) \[C@@H] (O) [C@@H] (OC) C (=O) [C@H] (C) C[C@H] (C) \C=C\C=C\C=C (C) \[C@H] (C2) OC) [C@H] (C) C[C@@H]1CC[C@H] ([C@@H] (C1) OC) n1cnnn1