(-) -Blebbistatin
(-) -Blebbistatin is the potent and selective S-enantiomeric inhibitor of myosin II isoforms, exhibiting IC50 values in the low micromolar range. It is widely employed in vitro to study cytoskeletal dynamics, cell division, and migration, and has been used in vivo to investigate cardiac function and muscle contraction mechanisms.
Product Specifications
CAS Number
856925-71-8
Product Name Alternative
Inhibitor, non-muscle myosin II ATPases, Myosin, inhibit, Blebbistatin, (S) - (-) -Blebbistatin, () Blebbistatin, () Blebbistatin
Field of Research
Pharmacology & Drug Discovery, Signal Transduction
Purity
99.38% (May vary between batches)
Solubility
DMSO:105 mg/mL (359.18 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.93 mg/mL (10.02 mM)
Smiles
Cc1ccc2N=C3N (CC[C@@]3 (O) C (=O) c2c1) c1ccccc1
Molecular Formula
C18H16N2O2
Molecular Weight
292.33
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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