[11C]MP 10
[11C]MP 10 (PF-2545920) is a highly potent and selective inhibitor of PDE10A, exhibiting an IC50 of 0.37 nM and >1000-fold selectivity over other PDEs. This radiolabeled tracer is used in preclinical and clinical PET imaging studies to investigate PDE10A expression and occupancy in the brain for neurological and psychiatric research.
Product Specifications
CAS Number
1292799-56-4
Product Name Alternative
[11C]MP 10, PDE10A, Mardepodect, PF2545920, PF-2545920, PF 2545920
Field of Research
Metabolism Research
Purity
99.50% (May vary between batches)
Solubility
Ethanol:69 mg/mL (176.27 mM) ; DMSO:79 mg/mL (201.81 mM)
Smiles
[11CH3]N1N=C (C (=C1) C=2C=CN=CC2) C3=CC=C (OCC4=NC5=C (C=C4) C=CC=C5) C=C3
Molecular Formula
C25H20N4O
Molecular Weight
391.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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