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PF-3845

PF-3845 is a potent and selective irreversible inhibitor of fatty acid amide hydrolase (FAAH), exhibiting a Ki of 230 nM with minimal activity against FAAH2. It is widely used as a pharmacological tool in vitro and in vivo to investigate the endocannabinoid system, pain, and inflammation.

Product Specifications

CAS Number

1196109-52-0

Product Name Alternative

Pain, inhibit, inflammation, Inhibitor, Fatty acid amide hydrolase, fatty, FAAH, hydrolase, depression, anxiety, amide, Autophagy, acid, PF-3845, PF3845, PF 3845, sensation

Field of Research

Cell Biology, Metabolism Research, Neuroscience

Purity

98.00% (May vary between batches)

Solubility

Ethanol:22.8 mg/mL (49.95 mM) ; DMSO:100 mg/mL (219.08 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.76 mM)

Smiles

FC (F) (F) c1ccc (Oc2cccc (CC3CCN (CC3) C (=O) Nc3cccnc3) c2) nc1

Molecular Formula

C24H23F3N4O2

Molecular Weight

456.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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