PF-3845
PF-3845 is a potent and selective irreversible inhibitor of fatty acid amide hydrolase (FAAH), exhibiting a Ki of 230 nM with minimal activity against FAAH2. It is widely used as a pharmacological tool in vitro and in vivo to investigate the endocannabinoid system, pain, and inflammation.
Product Specifications
CAS Number
1196109-52-0
Product Name Alternative
Pain, inhibit, inflammation, Inhibitor, Fatty acid amide hydrolase, fatty, FAAH, hydrolase, depression, anxiety, amide, Autophagy, acid, PF-3845, PF3845, PF 3845, sensation
Field of Research
Cell Biology, Metabolism Research, Neuroscience
Purity
98.00% (May vary between batches)
Solubility
Ethanol:22.8 mg/mL (49.95 mM) ; DMSO:100 mg/mL (219.08 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (8.76 mM)
Smiles
FC (F) (F) c1ccc (Oc2cccc (CC3CCN (CC3) C (=O) Nc3cccnc3) c2) nc1
Molecular Formula
C24H23F3N4O2
Molecular Weight
456.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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