Dalcetrapib
Dalcetrapib (RO4607381) is a potent inhibitor of cholesteryl ester transfer protein (CETP) with an IC50 of 0.2 μM. This small molecule elevates plasma HDL-C levels and has been utilized in cardiovascular research, including in vitro assays and clinical trials investigating atherosclerosis.
Product Specifications
CAS Number
211513-37-0
Product Name Alternative
HDL cholesterol, orally active, inhibit, JTT 705, JTT705, JTT-705, Inhibitor, Cholesteryl ester transfer protein, CETP, Dalcetrapib, RO4607381, RO-4607381, RO 4607381, rhCETP
Field of Research
Metabolism Research
Purity
97.98% (May vary between batches)
Solubility
DMSO:72 mg/mL (184.81 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:72 mg/mL (184.81 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.13 mM)
Smiles
CCC (CC) CC1 (CCCCC1) C (=O) Nc1ccccc1SC (=O) C (C) C
Molecular Formula
C23H35NO2S
Molecular Weight
389.59
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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