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SNS-032

SNS-032 is a potent and selective cyclin-dependent kinase inhibitor, primarily targeting CDK2 (IC50=48 nM), CDK7, and CDK9, with weaker activity against CDK1 and CDK4. It has been utilized in cancer research to study transcriptional regulation and cell cycle arrest in various in vitro and in vivo models.

Product Specifications

CAS Number

345627-80-7

Product Name Alternative

BMS 387032, BMS387032, BMS-387032, Apoptosis, Cyclin dependent kinase, CDK, CDK2/CyclinA, CDK2/CyclinE, CDK9/CyclinT, CDK7/CyclinH, inhibit, GSK3, GSK-3α, Inhibitor, SNS032, SNS-032, SNS 032

Field of Research

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.27% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM) ; DMSO:64.38 mg/mL (169.19 mM)

Smiles

C (SC=1SC (NC (=O) C2CCNCC2) =NC1) C=3OC (C (C) (C) C) =CN3

Molecular Formula

C17H24N4O2S2

Molecular Weight

380.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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