SNS-032
SNS-032 is a potent and selective cyclin-dependent kinase inhibitor, primarily targeting CDK2 (IC50=48 nM), CDK7, and CDK9, with weaker activity against CDK1 and CDK4. It has been utilized in cancer research to study transcriptional regulation and cell cycle arrest in various in vitro and in vivo models.
Product Specifications
CAS Number
345627-80-7
Product Name Alternative
BMS 387032, BMS387032, BMS-387032, Apoptosis, Cyclin dependent kinase, CDK, CDK2/CyclinA, CDK2/CyclinE, CDK9/CyclinT, CDK7/CyclinH, inhibit, GSK3, GSK-3α, Inhibitor, SNS032, SNS-032, SNS 032
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.27% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.26 mM) ; DMSO:64.38 mg/mL (169.19 mM)
Smiles
C (SC=1SC (NC (=O) C2CCNCC2) =NC1) C=3OC (C (C) (C) C) =CN3
Molecular Formula
C17H24N4O2S2
Molecular Weight
380.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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