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TAK-700

Orteronel (TAK-700) is a highly selective 17,20-lyase inhibitor with an IC50 of 38 nM, showing >1000-fold selectivity over related CYPs. It has been investigated in clinical research, including Phase 3 trials, for conditions like prostate cancer, where it targets androgen biosynthesis in both in vitro and in vivo models.

Product Specifications

CAS Number

426219-18-3

Product Name Alternative

Orteronel, 17,20-lyase (Human), 17,20-lyase (Rat), (S/R) -Orteronel, TAK 700, TAK700, TAK-700

Field of Research

Epigenetics & Chromatin, Metabolism Research

Purity

97.26% (May vary between batches)

Solubility

DMSO:57 mg/mL (185.46 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.25 mM) ; Ethanol:8 mg/mL (26.03 mM)

Smiles

OC1 (C=2N (CC1) C=NC2) C3=CC4=C (C=C3) C=C (C (NC) =O) C=C4

Molecular Formula

C18H17N3O2

Molecular Weight

307.35

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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