GW-441756
GW 441756 is a potent and selective small molecule inhibitor of the Tropomyosin-related kinase A (TrkA) receptor, exhibiting an IC50 of 2 nM. It is widely used in biochemical and cellular research to investigate TrkA signaling pathways in both in vitro and in vivo models of neurobiology and oncology.
Product Specifications
CAS Number
504433-23-2
Product Name Alternative
Tyrosine, Trkreceptor, TrkA, Trk Receptor, Trk receptor, Tropomyosin related kinase receptor, specific, receptor, potent, factor, growth, GW 441756, GW441756, GW-441756, Inhibitor, kinases, inhibit, NGF, nerve, Apoptosis, CDK2, C-Raf-1
Field of Research
Neuroscience
Purity
>98%
Bioactivity
NGFR kinase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 5 mg/ml) .
Smiles
Cn1cc (\C=C2/C (=O) Nc3cccnc23) c2ccccc12
Molecular Formula
C17H13N3O
Molecular Weight
275.31
Storage Conditions
RT
Notes
For research use only.
Other Product Names
1,3-Dihydro-3-[ (1-methyl-1H-indol-3-yl) methylene]-2H-pyrrolo[3,2-b]pyridin-2-one
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