Turofexorate Isopropyl
Turofexorate Isopropyl (XL335) is a potent, selective, and orally active FXR agonist exhibiting an EC50 of 4 nM. It is a valuable research tool for investigating FXR's role in metabolic diseases, including non-alcoholic steatohepatitis (NASH), and has demonstrated efficacy in both in vitro assays and in vivo preclinical models.
Product Specifications
CAS Number
629664-81-9
Product Name Alternative
Inhibit, NR1H4, Inhibitor, FXR, FXR 450, FXR450, FXR-450, Autophagy, XL 335, XL335, XL-335, WAY 362450, WAY362450, WAY-362450, Turofexorate Isopropyl
Field of Research
Cell Biology, Metabolism Research
Purity
98.55% (May vary between batches)
Solubility
DMSO:31 mg/mL (70.7 mM) ; Ethanol:2 mg/mL (4.56 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.56 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) OC (=O) C1=CN (CC (C) (C) c2c1[nH]c1ccccc21) C (=O) c1ccc (F) c (F) c1
Molecular Formula
C25H24F2N2O3
Molecular Weight
438.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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