URMC-099
URMC-099 is a potent, orally bioavailable, and brain-penetrant small molecule inhibitor targeting mixed-lineage kinases (MLKs) and LRRK2. It is widely used in preclinical research to investigate neuroinflammation, neurodegeneration, and lysosomal function in both cellular and animal models.
Product Specifications
CAS Number
1229582-33-5
Product Name Alternative
DNAAlkylation, DNA Alkylation, DLK, cMet, c-Met, cMet/HGFR, CDK2, CDK1, BcrAbl, Autophagy, Aurora A, Aurora B, AuroraKinase, Aurora C, Aurora Kinase, Abl1, IGF-1R, IGF1R, Inhibitor, Insulin Receptor, Lck, HGFR, MEKK2, inhibit, MLK1, MLK2, MLK3, MLKs, Mixed Lineage Kinase, LRRK2, URMC 099, URMC099, URMC-099, VEGFR1/FLT1, TrkA, Trk receptor, Trkreceptor, TrkB, Syk, ROCK1, ROCK2, SGK1, SGK
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience
Purity
>98%
Bioactivity
MLK3 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml)
Smiles
CN1CCN (Cc2ccc (cc2) -c2cnc3[nH]cc (-c4ccc5[nH]ccc5c4) c3c2) CC1
Molecular Formula
C27H27N5
Molecular Weight
421.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3- (1H-Indol-5-yl) -5- (4- ((4-methylpiperazin-1-yl) methyl) phenyl) -1H-pyrrolo[2,3-b]pyridine
Available Sizes
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