Brefeldin A
Brefeldin A is a macrolide antibiotic and potent ATPase inhibitor that induces tumor cell differentiation and apoptosis while also inhibiting autophagy. It is widely used in cancer research to study intracellular transport mechanisms in both cellular and animal models.
Product Specifications
CAS Number
20350-15-6
Product Name Alternative
Cas9, Brefeldin A, Cyanein, CRISPR/Cas9, CRISPR, Decumbin, BFA, Ascotoxin, ATPase (HCT 116), Autophagy, Antibiotic, inhibit, Mitochondrial Autophagy, Mitophagy, Inhibitor, Herpes simplex virus, HSV
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Inhibits intracellular transport
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 25 mg/ml) .
Smiles
[H][C@@]12C[C@H] (O) C[C@@]1 ([H]) [C@H] (O) \C=C\C (=O) O[C@@H] (C) CCC\C=C\2
Molecular Formula
C16H24O4
Molecular Weight
280.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
Fermentation product from Penicillium brefeldianum
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