(E/Z) -Rigosertib sodium
ON-01910 (Rigosertib) is a potent and selective non-ATP-competitive inhibitor of PLK1, demonstrating pro-apoptotic activity in cancer cells through PI3K/Akt pathway inhibition and oxidative stress induction. It is widely used in oncology research, with studies in both cellular and animal models exploring its mechanisms and therapeutic potential against various malignancies.
Product Specifications
CAS Number
1225497-78-8
Product Name Alternative
(E/Z) ON-01910 sodium, ON-01910, ON 01910, ON01910, PLK1
Field of Research
Cell Biology
Purity
97.16% (May vary between batches)
Solubility
DMSO:94 mg/mL (198.53 mM)
Smiles
[Na+].COc1cc (OC) c (C=CS (=O) (=O) Cc2ccc (OC) c (NCC ([O-]) =O) c2) c (OC) c1
Molecular Formula
C21H24NNaO8S
Molecular Weight
473.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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