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BGT226

BGT226 (NVP-BGT226) is a potent dual inhibitor of PI3K and mTOR, demonstrating high potency against PI3Kα, β, and γ isoforms. It is utilized in preclinical research to investigate oncogenic signaling pathways and has been studied in various cancer cell lines and in vivo tumor models.

Product Specifications

CAS Number

915020-55-2

Product Name Alternative

PI3K, PI3Kγ, PI3Kβ, PI3Kα, Autophagy, BGT 226, BGT226, BGT-226, BGT226 free base, mTOR, NVP-BGT 226, NVP-BGT226, NVP-BGT-226, Mammalian target of Rapamycin

Field of Research

Cell Biology, Signal Transduction

Purity

95.74% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.87 mM) ; DMSO:65 mg/mL (121.6 mM)

Smiles

COc1ccc (cn1) -c1ccc2ncc3n (C) c (=O) n (-c4ccc (N5CCNCC5) c (c4) C (F) (F) F) c3c2c1

Molecular Formula

C28H25F3N6O2

Molecular Weight

534.53

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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