Epothilone B
Epothilone B (Patupilone) is a microtubule-stabilizing agent isolated from Sorangium cellulosum. Unlike taxanes, it retains cytotoxicity against P-glycoprotein-overexpressing multidrug-resistant cells. It is widely used in cancer research, demonstrating antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
152044-54-7
Product Name Alternative
EPO-906; EpoBI; Patupilone
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Microtubule stabilizing agent
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml) .
Smiles
C[C@H]1CCC[C@@]2 (C) O[C@H]2C[C@H] (OC (=O) C[C@H] (O) C (C) (C) C (=O) [C@H] (C) [C@H]1O) C (\C) =C\c1csc (C) n1
Molecular Formula
C27H41NO6S
Molecular Weight
507.69
Storage Conditions
-20°C
Notes
For research use only.
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