Epothilone B
Epothilone B (Patupilone) is a microtubule-stabilizing agent isolated from Sorangium cellulosum. Unlike taxanes, it retains cytotoxicity against P-glycoprotein-overexpressing multidrug-resistant cells. It is widely used in cancer research, demonstrating antitumor activity in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
152044-54-7
Product Name Alternative
EPO-906; EpoBI; Patupilone
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Microtubule stabilizing agent
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 35 mg/ml) .
Smiles
C[C@H]1CCC[C@@]2 (C) O[C@H]2C[C@H] (OC (=O) C[C@H] (O) C (C) (C) C (=O) [C@H] (C) [C@H]1O) C (\C) =C\c1csc (C) n1
Molecular Formula
C27H41NO6S
Molecular Weight
507.69
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
NBP3-13797-20ug 20 µg
Mouse Monoclonal Carbonic Anhydrase VIII/CA8 Antibody (CA8/6572)
Sign In for Pricing
View Details 
N000063 30 Pack (30 Marker (s) x 1 Roll)
AC.CHLORHY.250X26RL-T1-LL-P21 Pipe Markers for Acids & Bases
Sign In for Pricing
View Details MBS6131074-01 0.1 mL
EHD4 (EH Domain-containing Protein 4, Hepatocellular Carcinoma-associated Protein 10/11, PAST Homolog 4, HCA10, HCA11, PAST4, FKSG7) (AP)
Sign In for Pricing
View Details MBS6131074-02 5x 0.1 mL
EHD4 (EH Domain-containing Protein 4, Hepatocellular Carcinoma-associated Protein 10/11, PAST Homolog 4, HCA10, HCA11, PAST4, FKSG7) (AP)
Sign In for Pricing
View Details