EPZ015666
EPZ015666 (GSK3235025) is a potent and selective small molecule inhibitor of protein arginine methyltransferase 5 (PRMT5) . It is orally bioavailable and has been utilized in both in vitro and in vivo research to investigate the role of PRMT5 in oncology, hematology, and other disease contexts.
Product Specifications
CAS Number
1616391-65-1
Product Name Alternative
PRMT5, GSK 3235025, GSK3235025, GSK-3235025, EPZ 015666, EPZ015666, EPZ-015666, Inhibitor, Histone Methyltransferase, HistoneMethyltransferase, inhibit
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
Potent and selective PRMT5 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
O[C@@H] (CNC (=O) c1cc (NC2COC2) ncn1) CN1CCc2ccccc2C1
Molecular Formula
C20H25N5O3
Molecular Weight
383.44
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(S) -N- (3- (3,4-Dihydroisoquinolin-2 (1H) -yl) -2-hydroxypropyl) -6- (oxetan-3-ylamino) pyrimidine-4-carboxamide
Available Sizes
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