AZD8330
AZD8330 (ARRY-704) is a potent and selective allosteric inhibitor of MEK1/2, demonstrating an IC50 of 7 nM. This investigational compound has been utilized in preclinical in vitro and in vivo studies to explore its potential in oncology research, particularly targeting the MAPK signaling pathway.
Product Specifications
CAS Number
869357-68-6
Product Name Alternative
MEK, MEK1/2, MAPKK, MAP2K, Inhibitor, ERK phosphorylation, Mitogen-activated protein kinase kinase, inhibit, AZD8330, AZD-8330, ARRY704, ARRY-704, ARRY424704, ARRY-424704, ARRY 704, ARRY 424704, AZD 8330
Field of Research
Signal Transduction
Purity
98.72% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:85 mg/mL (184.29 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.42 mM) ; Ethanol:85 mg/mL (184.29 mM)
Smiles
Cc1cc (C (=O) NOCCO) c (Nc2ccc (I) cc2F) n (C) c1=O
Molecular Formula
C16H17FIN3O4
Molecular Weight
461.23
Storage Conditions
-20°C
Notes
For research use only.
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