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AZD8330

AZD8330 (ARRY-704) is a potent and selective allosteric inhibitor of MEK1/2, demonstrating an IC50 of 7 nM. This investigational compound has been utilized in preclinical in vitro and in vivo studies to explore its potential in oncology research, particularly targeting the MAPK signaling pathway.

Product Specifications

CAS Number

869357-68-6

Product Name Alternative

MEK, MEK1/2, MAPKK, MAP2K, Inhibitor, ERK phosphorylation, Mitogen-activated protein kinase kinase, inhibit, AZD8330, AZD-8330, ARRY704, ARRY-704, ARRY424704, ARRY-424704, ARRY 704, ARRY 424704, AZD 8330

Field of Research

Signal Transduction

Purity

98.72% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:85 mg/mL (184.29 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (5.42 mM) ; Ethanol:85 mg/mL (184.29 mM)

Smiles

Cc1cc (C (=O) NOCCO) c (Nc2ccc (I) cc2F) n (C) c1=O

Molecular Formula

C16H17FIN3O4

Molecular Weight

461.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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