LY2603618
Rabusertib (IC-83) is a selective checkpoint kinase 1 (Chk1) inhibitor investigated for its chemosensitizing potential in oncology research. It has been evaluated in preclinical and clinical studies for solid tumors, including pancreatic and non-small cell lung cancers, to enhance the efficacy of DNA-damaging chemotherapeutic agents.
Product Specifications
CAS Number
911222-45-2
Product Name Alternative
Rabusertib
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Chk1 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml)
Smiles
Cc1cnc (NC (=O) Nc2cc (Br) c (C) cc2OC[C@@H]2CNCCO2) cn1
Molecular Formula
C18H22BrN5O3
Molecular Weight
436.30
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N-[5-bromo-4-methyl-2-[ (2S) -2-morpholinylmethoxy]phenyl]-N'- (5-methyl-2-pyrazinyl) urea
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