AZD-7762
AZD-7762 is a potent and selective ATP-competitive checkpoint kinase inhibitor, exhibiting an IC50 of 5 nM against Chk1 and similar potency against Chk2. It is widely used in cancer research to study DNA damage response pathways and has been evaluated in both in vitro and in vivo models to potentiate the effects of genotoxic agents.
Product Specifications
CAS Number
860352-01-8
Product Name Alternative
Chk2, Chk1, Checkpoint Kinase (Chk), AZD7762, AZD-7762, AZD 7762, Inhibitor, inhibit
Field of Research
Cell Biology
Purity
98.96% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.52 mM) ; DMSO:250 mg/mL (689.81 mM)
Smiles
NC (=O) Nc1cc (sc1C (=O) N[C@H]1CCCNC1) -c1cccc (F) c1
Molecular Formula
C17H19FN4O2S
Molecular Weight
362.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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