GKT-137831
Setanaxib (GKT137831) is a selective dual inhibitor targeting the NADPH oxidase isoforms NOX1 and NOX4. It is widely used in research to investigate the role of oxidative stress in fibrotic diseases, cancer, and diabetic nephropathy, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1218942-37-0
Product Name Alternative
Setanaxib; GKT-831
Field of Research
Immunology & Inflammation, Neuroscience
Purity
>98%
Bioactivity
NADPH oxidase NOX1/4 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 65 mg/ml)
Smiles
CN (C) c1cccc (c1) -c1n (C) c (=O) cc2[nH]n (-c3ccccc3Cl) c (=O) c12
Molecular Formula
C21H19ClN4O2
Molecular Weight
394.85
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2- (2-Chlorophenyl) -4-[3- (dimethylamino) phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6 (2H,5H) -dione
Available Sizes
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