Entospletinib
Entospletinib (GS-9973) is a potent and selective oral inhibitor of spleen tyrosine kinase (Syk) with an IC50 of 7.7 nM. It is a research tool for investigating hematological cancers and autoimmune disorders, showing activity in both cellular assays and animal models of disease.
Product Specifications
CAS Number
1229208-44-9
Product Name Alternative
Inhibit, Inhibitor, Entospletinib, GS 9973, GS9973, GS-9973, Syk, Spleen tyrosine kinase
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (6.08 mM) ; DMSO:50 mg/mL (121.52 mM)
Smiles
C1CN (CCO1) c1ccc (Nc2nc (cn3ccnc23) -c2ccc3cn[nH]c3c2) cc1
Molecular Formula
C23H21N7O
Molecular Weight
411.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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