Selinexor
Selinexor (KPT-330) is an orally bioavailable, selective inhibitor of Exportin 1 (XPO1/CRM1) . It induces cell cycle arrest and apoptosis, demonstrating antitumor activity in preclinical models of multiple myeloma, including both in vitro cell studies and in vivo xenograft experiments.
Product Specifications
CAS Number
1393477-72-9
Product Name Alternative
KPT-330
Field of Research
Neuroscience
Purity
>98%
Bioactivity
Inhibitor of the nuclear export receptor CRM1/XPO1
Form
Powder
Solubility
Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
Smiles
FC (F) (F) c1cc (cc (c1) C (F) (F) F) -c1ncn (\C=C/C (=O) NNc2cnccn2) n1
Molecular Formula
C17H11F6N7O
Molecular Weight
443.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(Z) -3-[3-[3,5-Bis (trifluoromethyl) phenyl]-1,2,4-triazol-1-yl]-N’-pyrazin-2-ylprop-2-enehydrazide
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