IU1
IU1 is a cell-permeable, reversible, and specific inhibitor of the human deubiquitinase USP14, with a reported IC50 of 4.7 μM. It is a valuable research tool for studying proteasome function, protein turnover, and neurodegenerative disease mechanisms in both cellular and biochemical assays.
Product Specifications
CAS Number
314245-33-5
Product Name Alternative
USP14, Inhibitor, inhibit, IU 1, IU1, IU-1, Autophagy, DUBs, Deubiquitinase
Field of Research
Protein Biochemistry
Purity
>98%
Bioactivity
USP-14 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml) .
Smiles
O=C (C=1C=C (N (C2=CC=C (F) C=C2) C1C) C) CN3CCCC3
Molecular Formula
C18H21FN2O
Molecular Weight
300.38
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[1- (4-Fluorophenyl) -2,5-dimethyl-1H-pyrrol-3-yl]-2- (1-pyrrolidinyl) ethanone
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
126095-ML405 100 µL
DYRK1A (Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1A, Protein Kinase Minibrain Homolog, MNBH, HP86, Dual Specificity YAK1-related Kinase, hMNB, DYRK, MNB, MNBH) (MaxLight 405) discontinued
Sign In for Pricing
View Details LV792841 1.0 µg DNA
SLC25A33 Lentiviral Vector (Human) (UbC) (pLenti-GIII-UbC)
Sign In for Pricing
View Details 
GTR15176418 1 Vial
Lentiviral mouse Mok shRNA (UAS) - Lentiviral mouse Mok shRNA (UAS) (100)
Sign In for Pricing
View Details 