Darapladib
Darapladib (SB-480848) is a potent and selective Lp-PLA2 inhibitor with an IC50 of 0.25 nM. It is widely used in cardiovascular disease research to study atherosclerosis mechanisms and has demonstrated protective effects in both in vitro assays and in vivo animal models.
Product Specifications
CAS Number
356057-34-6
Product Name Alternative
Darapladib, Inhibitor, Lp-PLA2, inhibit, Phospholipase, SB 480848, SB480848, SB-480848
Field of Research
Cell Biology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
DMSO:123.75 mg/mL (185.6 mM) ; Ethanol:93 mg/mL (139.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (6 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C (C (N (CC1=CC=C (C=C1) C2=CC=C (C (F) (F) F) C=C2) CCN (CC) CC) =O) N3C4=C (C (=O) N=C3SCC5=CC=C (F) C=C5) CCC4
Molecular Formula
C36H38F4N4O2S
Molecular Weight
666.77
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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