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YM-201636

YM201636 is a potent and selective PIKfyve inhibitor with an IC50 of 33 nM. It exhibits minimal activity against p110α and no effect on the yeast orthologue Fab1. This compound is a valuable research tool for studying lysosomal function and autophagy in cellular and animal models of related diseases.

Product Specifications

CAS Number

371942-69-7

Product Name Alternative

P110α, Inhibitor, Influenza Virus, InfluenzaVirus, inhibit, Fab1, Autophagy, Phosphoinositide 3-kinase, PIKfyve, PI3K, YM201636, YM-201636, YM 201636

Field of Research

Cell Biology, Infectious Disease & Virology, Signal Transduction

Purity

93.28% (May vary between batches)

Solubility

DMSO:13.33 mg/mL (28.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.28 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Cl.Nc1ccc (cn1) C (=O) Nc1cccc (c1) -c1nc (N2CCOCC2) c2oc3ncccc3c2n1

Molecular Formula

C25H21N7O3

Molecular Weight

467.48

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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