NVP-HSP990
NVP-HSP990 (HSP990) is a potent and selective HSP90α/β inhibitor with IC50 values of 0.6 nM and 0.8 nM, respectively. It is widely used in cancer research to study oncogenic client protein degradation and has demonstrated antitumor efficacy in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
934343-74-5
Product Name Alternative
NVP HSP990, NVP-HSP 990, NVPHSP990, NVP-HSP990, NVP-HSP-990, inhibit, Inhibitor, Heat shock proteins, HSP90α, HSP90β, HSP990, HSP-990, HSP 990, HSP, Apoptosis
Field of Research
Cell Biology, Metabolism Research, Signal Transduction
Purity
97.63% (May vary between batches)
Solubility
DMSO:70 mg/mL (184.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
COC1=CC=CC (=N1) C1=C (C=CC (F) =C1) C1CC2=C (C (C) =NC (N) =N2) C (=O) N1
Molecular Formula
C20H18FN5O2
Molecular Weight
379.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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