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JNJ-7706621

JNJ-7706621 is a dual-action small molecule inhibitor targeting aurora kinases as well as CDK1 and CDK2. It is utilized in cancer research to study cell cycle progression and mitotic events, demonstrating activity in both cellular assays and in vivo tumor models.

Product Specifications

CAS Number

443797-96-4

Product Name Alternative

Inhibit, JNJ 7706621, JNJ7706621, JNJ-7706621, Inhibitor, AuroraKinase, Aurora Kinase, Aurora A, Aurora B, Apoptosis, Cyclin dependent kinase, CDK2/CyclinA, CDK1/CyclinB, CDK, CDK2/CyclinE

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

99.10% (May vary between batches)

Solubility

DMSO:55 mg/mL (139.47 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.07 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Nc1nc (Nc2ccc (cc2) S (N) (=O) =O) nn1C (=O) c1c (F) cccc1F

Molecular Formula

C15H12F2N6O3S

Molecular Weight

394.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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