YO-01027
YO-01027 (DBZ) is a potent and selective γ-secretase inhibitor used in research to modulate Notch signaling. It is applied in both in vitro and in vivo studies investigating pathways involved in cancer, neurology, and developmental biology.
Product Specifications
CAS Number
209984-56-5
Product Name Alternative
Dibenzazepine, DBZ, Inhibitor, Gammasecretase, gamma-Secretase Inhibitor XX, Gamma secretase, inhibit, Notch, γ secretase (Notch), γ secretase (APPL), γ-secretase, YO 01027, YO01027, YO-01027
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Purity
97.21% (May vary between batches)
Solubility
DMSO:46.4 mg/mL (100.11 mM) ;10% DMSO+90% Corn Oil:2 mg/mL (4.32 mM)
Smiles
C[C@H] (NC (=O) Cc1cc (F) cc (F) c1) C (=O) N[C@H]1c2ccccc2-c2ccccc2N (C) C1=O
Molecular Formula
C26H23F2N3O3
Molecular Weight
463.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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