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KRN-633

KRN-633 is a potent small molecule inhibitor targeting vascular endothelial growth factor receptors (VEGFRs), with IC50 values of 170 nM for VEGFR1, 160 nM for VEGFR2, and 125 nM for VEGFR3. It is widely used in preclinical research to study angiogenesis and tumor growth in both cellular assays and animal models.

Product Specifications

CAS Number

286370-15-8

Product Name Alternative

Inhibitor, KRN 633, KRN633, KRN-633, inhibit, VEGFR1, VEGFR, VEGFR3, VEGFR2, Vascular endothelial growth factor receptor

Field of Research

Cardiovascular Research, Signal Transduction

Purity

99.22% (May vary between batches)

Solubility

DMSO:6 mg/mL (14.39 mM)

Smiles

CCCNC (=O) Nc1ccc (Oc2ncnc3cc (OC) c (OC) cc23) cc1Cl

Molecular Formula

C20H21ClN4O4

Molecular Weight

416.86

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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