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A-674563 2HCl (552325-73-2 (fb-2hcl) )

A-674563 2HCl is a potent and selective Akt1 inhibitor with a Ki of 11 nM. It exhibits modest activity against PKA and over 30-fold selectivity versus PKC. This tool compound is used in vitro and in vivo to study the PI3K/Akt signaling pathway in cancer and metabolic research.

Product Specifications

Product Name Alternative

CDK2, A-674563 2HCl (552325-73-2 (fb-2hcl) ), A674563 2HCl (552325732 (fb2hcl) ), A 674563 2HCl (552325 73 2 (fb 2hcl) ), Akt1, ERK2, PKA, PKCδ

Field of Research

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Purity

94.66% (May vary between batches)

Solubility

DMSO:27.5 mg/mL (63.75 mM)

Smiles

Cl.Cl.Cc1n[nH]c2ccc (cc12) -c1cncc (OC[C@@H] (N) Cc2ccccc2) c1

Molecular Formula

C22H24Cl2N4O

Molecular Weight

431.36

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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