A-674563 2HCl (552325-73-2 (fb-2hcl) )
A-674563 2HCl is a potent and selective Akt1 inhibitor with a Ki of 11 nM. It exhibits modest activity against PKA and over 30-fold selectivity versus PKC. This tool compound is used in vitro and in vivo to study the PI3K/Akt signaling pathway in cancer and metabolic research.
Product Specifications
Product Name Alternative
CDK2, A-674563 2HCl (552325-73-2 (fb-2hcl) ), A674563 2HCl (552325732 (fb2hcl) ), A 674563 2HCl (552325 73 2 (fb 2hcl) ), Akt1, ERK2, PKA, PKCδ
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
94.66% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (63.75 mM)
Smiles
Cl.Cl.Cc1n[nH]c2ccc (cc12) -c1cncc (OC[C@@H] (N) Cc2ccccc2) c1
Molecular Formula
C22H24Cl2N4O
Molecular Weight
431.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC472844-100 1x 100 µL
Spastin (Sp 3G11-1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
LY402408 100 µg
MAST205 (MAST2) (NM_015112) Human Over-expression Lysate
Sign In for Pricing
View Details 
BNC402865-500 1x 500 µL
VISTA / GI24 (Negative Regulator of Immune Response) (VISTA/2865), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details