SB-334867 free base
SB-334867 free base is a selective orexin-1 (OX1) receptor antagonist with a pKi of 7.17 for the human OX1 receptor. It is widely used in research to investigate orexin signaling in sleep/wake regulation, addiction, and stress responses, employing both in vitro cellular assays and in vivo behavioral models.
Product Specifications
CAS Number
792173-99-0
Product Name Alternative
Activity, BEC, cell, CHO, locomotor, inhibit, Orexin Receptor (OX Receptor), OX Receptor, OX1, Hypocretin Receptor, Inhibitor, intake, HCRT Receptor, ethanol, sucrose, SB 334867, SB 334867 free base, SB334867, SB-334867, SB334867 free base, SB-334867 free base, SB334867A, SB334867A free base, OXReceptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.67% (May vary between batches)
Solubility
DMSO:31.9 mg/mL (99.9 mM) ; Ethanol:3.2 mg/mL (10.02 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.26 mM)
Smiles
N (C (NC=1C=C2C (=CC1) N=C (C) O2) =O) C=3C4=C (N=CC3) C=CC=N4
Molecular Formula
C17H13N5O2
Molecular Weight
319.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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