Dorsomorphin dihydrochloride

Dorsomorphin dihydrochloride (BML-275 2HCl) is a selective, ATP-competitive AMPK inhibitor (Ki=109 nM) that also blocks BMP receptors ALK2, ALK3, and ALK6. This compound induces autophagy and exhibits antitumor activity, making it a valuable tool for studying metabolic signaling, bone morphogenesis, and cancer biology in both cellular and animal models.

Product Specifications

CAS Number

1219168-18-9

Product Name Alternative

Inhibit, pathway, Inhibitor, Compound C Dihydrochloride, Compound C, Compound C 2HCl, Compound C dihydrochloride, Dorsomorphin, Dorsomorphin (Compound C), Dorsomorphin Dihydrochloride, Dorsomorphin dihydrochloride, Dorsomorphin (Compound C) 2HCl, AMPK, AMP-activated protein kinase, Autophagy, ATP-competitive, BML 275, BML 275 Dihydrochloride, BML275, BML-275, BML-275 2HCl, BML275 Dihydrochloride, BML-275 Dihydrochloride, BML-275 dihydrochloride, BMP, receptors, Smad, type, Transforming growth factor beta receptors, TGF-b/Smad, TGFb, TGFbeta/Smad, TGF-beta, TGFbeta, TGFβ, TGF-β Receptor, TGF-β/Smad