SU11274
SU11274 is a potent and selective Met kinase inhibitor with an IC50 of 10 nM. It demonstrates minimal activity against related kinases such as PGDFRβ, EGFR, and Tie2. This inhibitor is widely used in cancer research for in vitro and in vivo studies investigating Met-driven tumorigenesis and metastasis.
Product Specifications
CAS Number
658084-23-2
Product Name Alternative
CDK2, c-Met/HGFR, cMet, c-Met, cMet/HGFR, Autophagy, Apoptosis, Met, Met Kinase Inhibitor, HGFR, Flk1, FGFR1, PKI-SU 11274, PKI-SU11274, PKI-SU-11274, RON, SU11274, SU-11274, SU 11274
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.62% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.81 mM) ; Ethanol:2 mg/mL (3.52 mM) ; DMSO:48.33 mg/mL (85.07 mM)
Smiles
C (=C\1/C=2C (NC1=O) =CC=C (S (N (C) C3=CC (Cl) =CC=C3) (=O) =O) C2) \C4=C (C) C (C (=O) N5CCN (C) CC5) =C (C) N4
Molecular Formula
C28H30ClN5O4S
Molecular Weight
568.09
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2149501-01 0.1 mL
PE-Linked Monoclonal Antibody to Stanniocalcin 1 (STC1)
Sign In for Pricing
View Details MBS2149501-02 0.2 mL
PE-Linked Monoclonal Antibody to Stanniocalcin 1 (STC1)
Sign In for Pricing
View Details MBS2149501-03 0.5 mL
PE-Linked Monoclonal Antibody to Stanniocalcin 1 (STC1)
Sign In for Pricing
View Details MBS2149501-04 1 mL
PE-Linked Monoclonal Antibody to Stanniocalcin 1 (STC1)
Sign In for Pricing
View Details MBS2149501-05 5 mL
PE-Linked Monoclonal Antibody to Stanniocalcin 1 (STC1)
Sign In for Pricing
View Details MBS2149501-06 5x 5 mL
PE-Linked Monoclonal Antibody to Stanniocalcin 1 (STC1)
Sign In for Pricing
View Details