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BS-181 hydrochloride

BS-181 hydrochloride is a potent and selective CDK7 inhibitor (IC50 = 21 nM), demonstrating over 40-fold selectivity against CDK1, 2, 4, 5, 6, and 9. It is a valuable research tool for studying transcriptional regulation, cell cycle progression, and has been utilized in both in vitro and in vivo cancer model studies.

Product Specifications

CAS Number

1397219-81-6

Product Name Alternative

Inhibit, Inhibitor, BS 181, BS 181 hydrochloride, BS 181 Hydrochloride, BS181, BS-181, BS-181 HCl, BS181 Hydrochloride, BS181 hydrochloride, BS-181 Hydrochloride, CDK7, CDK, Cyclin dependent kinase

Field of Research

Cell Biology

Purity

99.21% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.59 mM) ; H2O:50 mg/mL (119.91 mM) ; Ethanol:22 mg/mL (52.76 mM) ; DMSO:100 mg/mL (239.81 mM)

Smiles

Cl.CC (C) c1cnn2c (NCc3ccccc3) cc (NCCCCCCN) nc12

Molecular Formula

C22H32N6·HCl

Molecular Weight

416.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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