Salirasib (FTS)
Salirasib (Farnesyl Thiosalicylic Acid) is a competitive PPMTase inhibitor with a Ki of 2.6 μM, blocking Ras methylation. This activity underlies its investigated antineoplastic potential, as demonstrated in studies targeting Ras-driven cancers in both cellular and animal models.
Product Specifications
CAS Number
162520-00-5
Product Name Alternative
Autophagy, FTS, Farnesyl Thiosalicylic Acid, Inhibitor, inhibit, Ras, S-Farnesylthiosalicylic acid, PPMTase, Salirasib
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Ras inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml) oe in Ethanol (up to 20 mg/ml)
Smiles
CC (C) =CCC\C (C) =C\CC\C (C) =C\CSc1ccccc1C (O) =O
Molecular Formula
C22H30O2S
Molecular Weight
358.54
Storage Conditions
RT
Notes
For research use only.
Other Product Names
Trans-Farnesylthiosalicylic acid
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