Telatinib
Telatinib (Bay 57-9352) is a potent small molecule inhibitor targeting VEGFR2/3, c-Kit, and PDGFRα with IC50 values of 6 nM/4 nM, 1 nM, and 15 nM, respectively. It is widely used in preclinical research for studying angiogenesis and tumor growth in both cellular assays and animal models.
Product Specifications
CAS Number
332012-40-5
Product Name Alternative
SCFR, Telatinib, PDGFR, PDGFRα, Vascular endothelial growth factor receptor, VEGFR, VEGFR3, VEGFR2, inhibit, Platelet-derived growth factor receptor, Inhibitor, Bay 57-9352, c-Kit, cKit, CD117
Field of Research
Cardiovascular Research, Signal Transduction
Purity
97.61% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:3.3 mg/mL (8.05 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:1 mg/mL (2.44 mM) ; DMSO:76 mg/mL (185.44 mM)
Smiles
CNC (=O) c1cc (COc2nnc (Nc3ccc (Cl) cc3) c3ccoc23) ccn1
Molecular Formula
C20H16ClN5O3
Molecular Weight
409.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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