IKK 16
IKK Inhibitor VII is a potent and selective small molecule inhibitor of IκB kinase, with greatest potency against IKK-2 (IC50 = 40 nM) . This compound is a valuable research tool for studying NF-κB signaling in cellular models of inflammation, immunity, and cancer.
Product Specifications
CAS Number
873225-46-8
Product Name Alternative
LRRK2, IκB kinase, IκB, Inhibitor, inhibit, IKK16, IKK-16, IKK2, IKK Inhibitor VII, IKK1, IKK 16, IKK, IkB/IKK, IkB, Leucine-rich repeat kinase 2, I kappa B kinase
Field of Research
Cell Biology, Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
95.01% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.82 mM) ; DMSO:23.64 mg/mL (48.88 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
O=C (N1CCC (CC1) N1CCCC1) c1ccc (Nc2nccc (n2) -c2cc3ccccc3s2) cc1
Molecular Formula
C28H29N5OS
Molecular Weight
483.63
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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