UPF-1069
UPF 1069 is a potent and selective inhibitor of PARP2, exhibiting an IC50 of 0.3 μM with approximately 27-fold selectivity over PARP1. This compound is a valuable chemical probe for studying PARP2-specific functions in DNA repair pathways and has been utilized in both cellular and animal models of relevant diseases.
Product Specifications
CAS Number
1048371-03-4
Product Name Alternative
Inhibitor, inhibit, PARP, PARP2, PARP1, UPF1069, UPF-1069, UPF 1069, poly ADP ribose polymerase
Field of Research
Cell Biology
Purity
>98%
Bioactivity
PARP-2 inhibitor
Form
Powder
Solubility
Soluble in DMSO up to 40 mg/ml
Smiles
O=C (COc1cccc2c1cc[nH]c2=O) c1ccccc1
Molecular Formula
C17H13NO3
Molecular Weight
279.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5- (2-Oxo-3-phenylethoxy) -1 (2H) -isoquinolinone
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