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UPF-1069

UPF 1069 is a potent and selective inhibitor of PARP2, exhibiting an IC50 of 0.3 μM with approximately 27-fold selectivity over PARP1. This compound is a valuable chemical probe for studying PARP2-specific functions in DNA repair pathways and has been utilized in both cellular and animal models of relevant diseases.

Product Specifications

CAS Number

1048371-03-4

Product Name Alternative

Inhibitor, inhibit, PARP, PARP2, PARP1, UPF1069, UPF-1069, UPF 1069, poly ADP ribose polymerase

Field of Research

Cell Biology

Purity

>98%

Bioactivity

PARP-2 inhibitor

Form

Powder

Solubility

Soluble in DMSO up to 40 mg/ml

Smiles

O=C (COc1cccc2c1cc[nH]c2=O) c1ccccc1

Molecular Formula

C17H13NO3

Molecular Weight

279.3

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

5- (2-Oxo-3-phenylethoxy) -1 (2H) -isoquinolinone

Available Sizes

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