MLS1547
MLS1547 is a potent and selective G protein-biased agonist of the dopamine D2 receptor, exhibiting a Ki of 1.2 μM. It activates G protein-mediated signaling with an EC50 of 0.37 μM in calcium flux assays, making it a valuable research tool for studying biased signaling in neuropharmacology, including in vitro models of psychiatric and neurological disorders.
Product Specifications
CAS Number
315698-36-3
Product Name Alternative
MLS1547, MLS-1547, MLS 1547, MLS 000051547, MLS000051547, MLS-000051547, Inhibitor, inhibit, biased, Dopamine Receptor, DopamineReceptor, D2 receptor, protein, recruitment, signaling, β-arrestin
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.02% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.82 mM) ; DMSO:45 mg/mL (126.82 mM)
Smiles
Oc1c (CN2CCN (CC2) c2ccccn2) cc (Cl) c2cccnc12
Molecular Formula
C19H19ClN4O
Molecular Weight
354.83
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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