NGB 2904
NGB 2904 is a highly selective dopamine D3 receptor antagonist with a Ki of 1.4 nM, exhibiting over 150-fold selectivity versus the D2 receptor. It potently inhibits quinpirole-stimulated mitogenesis (IC50 = 6.8 nM) and is a valuable research tool for investigating D3 receptor function in neuropsychiatric disorders and addiction models, both in vitro and in vivo.
Product Specifications
CAS Number
189060-98-8
Product Name Alternative
5HTReceptor, addiction, 5-HT2, 5HT Receptor, D1, D2, D4, D3, D5, DopamineReceptor, Dopamine Receptor, Dopamine, cocaine, NGB2904, NGB-2904, α1 receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.79% (May vary between batches)
Solubility
DMSO:16.25 mg/mL (32.86 mM)
Smiles
Clc1cccc (N2CCN (CCCCNC (=O) c3ccc-4c (Cc5ccccc-45) c3) CC2) c1Cl
Molecular Formula
C28H29Cl2N3O
Molecular Weight
494.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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