5-Hydroxy-1-methylhydantoin
5-Hydroxy-1-methylhydantoin (HD-003) is a creatinine-derived antioxidant and hydroxyl radical scavenger studied for renal and vascular protection. Research indicates it suppresses high glucose-induced B2KR expression and attenuates bradykinin-driven MAPK/CTGF signaling in VSMCs, demonstrating potential in models of diabetic nephropathy and vascular remodeling.
Product Specifications
CAS Number
84210-26-4
Product Name Alternative
5 Hydroxy 1 methylhydantoin, 5Hydroxy1methylhydantoin, 5-Hydroxy-1-methylhydantoin, Bradykinin Receptor, BradykininReceptor, bradykinin B2, HD 003, HD003, HD-003, NZ 419, NZ419, NZ-419
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.50% (May vary between batches)
Solubility
DMSO:60 mg/mL (461.18 mM)
Smiles
OC1N (C) C (=O) NC1=O
Molecular Formula
C4H6N2O3
Molecular Weight
130.1
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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