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Betulinic acid

Betulinic acid (ALS-357) is a lupane-type triterpene derived from birch bark, exhibiting antiretroviral, antimalarial, and anti-inflammatory activities. Its anticancer potential, studied in vitro and in vivo, is linked to topoisomerase inhibition, making it a compound of interest for oncology and infectious disease research.

Product Specifications

CAS Number

472-15-1

Product Name Alternative

Topoisomerase, NF-kB, NFkB, NFκB, NF-κB, Nuclear factor-κB, Nuclear factor-kappaB, Mitochondrial Autophagy, Mitophagy, Lupatic acid, inhibit, Endogenous Metabolite, EndogenousMetabolite, Eukaryotic topoisomerase I, Inhibitor, Human immunodeficiency virus, HIVProtease, HIV-1, HIV Protease, HIV, Betulic acid, Betulinic acid, Apoptosis, Autophagy, ALS357, ALS-357, ALS 357, Aminopeptidase N

Field of Research

Cell Biology

Purity

>98%

Bioactivity

Mitochondrial permeability pore activator

Form

Powder

Solubility

Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml) .

Smiles

C (O) (=O) [C@]12[C@@] ([C@@]3 ([C@@] (C) (CC1) [C@@]4 (C) [C@] (CC3) ([C@]5 (C) [C@@] (CC4) (C (C) (C) [C@@H] (O) CC5) [H]) [H]) [H]) ([C@H] (C (C) =C) CC2) [H]

Molecular Formula

C30H48O3

Molecular Weight

456.72

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

3ß-Hydroxy-20 (29) -lupaene-28-oic acid

Available Sizes

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