Pyrazoloacridine
Pyrazoloacridine (PD 115934) is a dual topoisomerase I/II inhibitor with an IC50 of 1.25 μM in K562 cells. This nucleic acid-binding agent exhibits anticancer activity and has been investigated in both in vitro cytotoxicity assays and in vivo preclinical tumor models.
Product Specifications
CAS Number
99009-20-8
Product Name Alternative
Apoptosis, carcinoma, Inhibitor, NSC366140, NSC-366140, NSC 366140, myeloid, inhibit, Pyrazoloacridine, pancreatic, PD115934, PD-115934, PD 115,934, PD 115934, leukemia, solid, tumor, Topo I, Topo II, Topoisomerase
Field of Research
Cell Biology, Molecular Biology
Purity
98.99% (May vary between batches)
Solubility
DMSO:5.22 mg/mL (14.21 mM)
Smiles
COc1ccc2[nH]c3c (ccc4n (CCCN (C) C) nc (c34) c2c1) [N+] ([O-]) =O
Molecular Formula
C19H21N5O3
Molecular Weight
367.4
Storage Conditions
-20°C
Notes
For research use only.
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