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Daphnetin

Daphnetin (7,8-Dihydroxycoumarin) is a natural protein kinase inhibitor targeting EGFR, PKA, and PKC. It also possesses antioxidant and anti-inflammatory properties, supporting its investigation in cellular assays and animal models for oncology and inflammatory disease research.

Product Specifications

CAS Number

486-35-1

Product Name Alternative

Daphnetin, Daphnetol, 7,8-Dihydroxycoumarin, A2780 cells, AMP-activated protein kinase, Akt, Caspase, Bcl-2 Family, Autophagy, Apoptosis, AMPK, inflammation, mTOR, inhibit, PARP, Parasite, Epidermal growth factor receptor, ErbB-1, EGFR, Inhibitor, HER1, Mammalian target of Rapamycin, schizontocidal, poly ADP ribose polymerase, Protein kinase C, Protein kinase B, protein kinase, Protein kinase A, PKC, PKB, PKA, Reactive Oxygen Species

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction

Purity

97.47% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.23 mM) ; DMSO:50 mg/mL (280.68 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Oc1ccc2ccc (=O) oc2c1O

Molecular Formula

C9H6O4

Molecular Weight

178.14

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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